通过光纤光度记录法，研究实时监测到抑郁样小鼠内侧前额叶在应激刺激下的多巴胺释放反应显著减弱。同时，实验证实，从VTA投射至内侧前额叶的多巴胺能神经元数量也呈减少趋势。完整揭示了肠道菌群参与该通路功能与结构同步受损的机制。

Bipolar disorder (BD) is a psychiatric disorder characterized by extreme mood changes. Individuals diagnosed with BD ...

Researchers from the Indiana University School of Medicine are one step closer to an objective clinical blood test for mood disorders. A robust new study is describing the development of a panel of ...

If you have bipolar I, you likely know how exhausting its highs and lows can be. In a depressive period, you might feel so down that you don’t want to do things you normally enjoy, or even leave your ...

The approval was supported by data from two phase 3 studies that evaluated Caplyta as monotherapy and adjunctive therapy with lithium or valproate in adults with bipolar depression. The Food and Drug ...

Dr. Harold Koenig answers the question: 'What Is Depression?' — -- Question: What is the difference between depression and manic depression (bipolar disorder)? Answer: Depression and manic ...

The US Food and Drug Administration (FDA) has expanded approval of lumateperone (Caplyta) to include treatment of adults with depressive episodes associated with bipolar I and II disorder, as ...

A new review article published in the journal JAMA Psychiatry is suggesting a number of different psychiatric disorders share common gut microbiome perturbations. The meta-analysis found depression, ...

Please provide your email address to receive an email when new articles are posted on . Researchers have uncovered important factors associated with the switch from mania to depression among ...

Unipolar depression is a mental health condition that involves a low, sad, or hopeless mood. The term “unipolar,” which comes from the roots “uni” (one) and “polar” (end), means you have symptoms from ...