Nerve cells communicate with each other by means of electrical impulses. To create such an impulse, the cells exchange charged ions with their environment. However, the role played by the ever-present ...
Nerve cells communicate with each other by means of electrical impulses. To create such an impulse, the cells exchange charged ions with their environment. However, the role played by the ever-present ...
Chloride channels, particularly those of the CLC family, are vital for cellular homeostasis by facilitating the exchange of chloride ions and protons across membranes. These transport proteins govern ...
Ion channels, most simply, are proteins that form pores in cell membranes that may permit the free passage of certain ions. These channels are broadly divided into those that selectively conduct ...
This is a preview. Log in through your library . Abstract The physiologically indispensable chloride channel (CLC) family is split into two classes of membrane proteins: chloride channels and chloride ...
In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems. Special channels in the cell membrane selectively permit salt ions to flow in and out ...
Rodent ClC-K1 and ClC-K2, and their respective human orthologs ClCKA and ClCKB, are chloride channels specific to the kidney (and inner ear); Barttin is their functionally important subunit. ClC-K1 is ...
Scientists have generated structural images of a newly-described class of ion channels that help maintain the balance of pH inside brain cells. These molecular gates, called proton-activated chloride ...
When the adrenal gland produces too much aldosterone, this often leads to high blood pressure and kidney damage (hyperaldosteronism). It has only recently emerged that several patients harbor a ...
In the cells of the Arabidopsis plant, exposure to sodium chloride (NaCl) induces the movement (translocation) of the green fluorescent protein (GFP) tagged chloride channel, GFP-AtCLCf, from the ...
Laboratory cell experiments and computer simulations have revealed molecular mechanisms regulating a protein channel responsible for transporting chloride and other charged molecules across cell ...
Mucous cell hyperplasia and airway smooth muscle (ASM) hyperresponsiveness are hallmark features of inflammatory airway diseases, including asthma. Here, we show that the recently identified ...
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