Imagining that protein stability needs to be kept within some limits for biological function is easy. However, is there any corresponding pressure on protein folding and, hence, the dynamic ...

Chromosome engineering is a major focus in the fields of systems biology, genetics, synthetic biology, and the functional analysis of genomes. Here, we describe the "telomerator," a new synthetic ...

Circular arrangement is one of the interesting topics of Permutations. Before understanding circular arrangement let us review some important concepts of linear ...

Figure 1: The permutation-by-duplication model is presumed to account for the evolution of various classes of DNA methyltransferases. Figure 2: Reproducing the first two steps of the ...

Using a technique called circular permutation, researchers at the University of California Berkeley have created a new suite of Cas9 variants called Cas9-CPs, which will simplify design of Cas9-fusion ...