12月31日，北京大学以“FOCAS: Transcriptome-wide screening of individual m6A sites functionally dissects epitranscriptomic control of ...

Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

This study presents SynaptoGen, a differentiable extension of connectome models that links gene expression, protein-protein interaction probabilities, synaptic multiplicity, and synaptic weights, and ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

What if you could flip a genetic switch to silence a gene, then turn it back on with a simple drug? For researchers, gene-switch tools offer that kind of control—and a new system called Cyclone may ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

Genes make up the blueprints and outline the process of building every living organism. To ensure that the right genes are activated in the right cells, and in the right amounts at the right time, ...

Artificial intelligence has just redrawn the map of our genome’s control room, revealing hundreds of thousands of tiny DNA ...

Scientists mapped hidden DNA switches in brain support cells to understand how gene control may influence Alzheimer’s disease ...

New method ASPEN accurately maps gene activity from each parent in individual cells, overcoming noise in data. It revealed ...

A multi-omics study identifies causal genes and biological subtypes of long COVID, revealing new therapeutic targets for ...