Nature

MT1-MMP is the critical determinant of matrix degradation and invasion by ovarian cancer cells

Membrane-type 1 matrix metalloproteinase (MT1-MMP), a transmembrane metalloprotease that plays an important role in the invasion of many solid tumour types, promotes pericellular matrix degradation ...
Nature

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

Epithelial cells are dependent on interactions with specific ECM components for survival, proliferation and differentiation functions 5. Loss of matrix attachment of cultured epithelial cells ...