有些生物虽在千万年前分道扬镳,却仍暗藏“藕断丝连”的进化密码——它们形态相近、核心发育程序稳定,却在分子层面悄然分化,成为解锁“进化如何平衡保守与创新”的关键线索。
Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...
Northwestern Medicine scientists have discovered how molecular "traffic controllers" in cells influence aging and cellular ...
New method ASPEN accurately maps gene activity from each parent in individual cells, overcoming noise in data. It revealed ...
SMRTS, a smart mRNA system, enables cell‑selective gene expression, expanding the mRNA toolbox for precision cancer therapies.
It's a common storytelling trope: the stubborn foe who is eventually revealed to be a much-needed friend. Biology has its own ...
Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...
A shared molecular signature of Alzheimer’s appears across populations once studied in isolation. Alzheimer's disease (AD) affects African Americans (AA) at roughly twice the rate seen among ...
Representative images and heatmaps illustrate how human fetal tooth germs from the upper and lower jaws, although morphologically similar at the cap stage, already display distinct gene expression ...