One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

Gene regulation and chromatin dynamics constitute central themes in modern molecular biology, governing how the genetic blueprint is accessed and utilised during development, differentiation and ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers in ...

Researchers identify a shared RNA-protein interaction that could lead to broad-spectrum antiviral treatments for ...

Before cells can divide, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Until now, scientists had believed that ...

DNA might be too small to see with the unaided eye, but it packs our cells in shocking quantities: More than six and a half feet of DNA lies within every cellular nucleus. It squeezes into such a ...

A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues and ...