One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose ...

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

Visualization of the genome (green) and a single gene (magenta) in a human cell nucleus, with genomic motions mapped by arrows and an example of a gene trajectory highlighted as a colored curve. A ...

Researchers have developed a tool that can bend DNA strands using light. The work represents a new way to probe the genome. Shown here, from an unrelated study, are chromosomes (blue) inside a human ...

In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

Bone implants often fail to fully integrate with surrounding tissue, limiting their effectiveness in regeneration. A natural but often overlooked cellular process could hold the key to better outcomes ...

Investigators from the laboratory of Derek Walsh, Ph.D., professor of Microbiology-Immunology, have discovered how human ...