One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

The research represents a major step forward in revealing how the three dimensional form of DNA shapes the way human biology functions. In a major step toward understanding how the physical form of ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to ...

Visualization of the genome (green) and a single gene (magenta) in a human cell nucleus, with genomic motions mapped by arrows and an example of a gene trajectory highlighted as a colored curve. A ...

DNA inside human cells is not just floating around freely. It is tightly wrapped around small proteins, forming a long chain.

In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

Bone implants often fail to fully integrate with surrounding tissue, limiting their effectiveness in regeneration. A natural but often overlooked cellular process could hold the key to better outcomes ...