Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

Much the way the caps on the ends of a shoelace prevent it from fraying, telomeres - regions of repetitive DNA sequences and a protein structure - protect the tips of chromosomes from damage. Every ...

Researchers created the most detailed maps yet of the genome’s three-dimensional organization using human stem cells and ...

A research team has successfully identified a novel DNA damage repair pathway in human cells. This study is the first to discover that proteins present in the nuclear membrane of cells directly ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

Researchers have revealed that so-called “junk DNA” contains powerful switches that help control brain cells linked to Alzheimer’s disease. By experimentally testing nearly 1,000 DNA switches in human ...