The current method to create a chimeric murine embryo involves engrafting cells from a separate donor embryo. But, in December 10 online Nature Genetics, Pentao Liu and colleagues at The National ...

Our facility analyzes the engraftment of a variety of stem cells in vivo, the effects of genetic modification of stem cells on engraftment and stem cell function, and the behavioral consequences of ...

Cells contain a blueprint in the form of DNA that dictates what they can make. This blueprint is converted into a message, or mRNA, which is then converted into protein. Although DNA remains the same ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

For the first time, researchers have transplanted gene-edited donor islet cells that secrete insulin in a person with type 1 diabetes (T1D) without the use of immunosuppression. The study subject, a ...

Specifically, the team confirmed that increased expression of cytoskeleton-binding and actin-binding proteins leads to a stable restructuring of the internal cellular architecture. This provides the ...