This is an important study on the sensory roles of Cerebrospinal fluid-contacting neurons (CBF-cn) in mammals. The authors identify PKD2L1 as the predominant pH-sensing channel CBF-cn and show how the ...

Motor neurons innervate muscle cells to control various voluntary and involuntary movements. The progressive degeneration of motor neurons is the core of neuromuscular disorders, such as ALS. AxoCells ...

Motor neurons are some of the largest cells in the human body. In particular, upper neurons—extending from the cerebral cortex to the brain stem or spinal cord—average 60μm in diameter. 3,4 These ...

Despite the pivotal role of motor neurons in movement, how a single motor neuron contributes to control during movement remains unclear. Measuring the activity of individual neurons in moving animals ...

Human induced pluripotent stem cell (iPSC)-derived motor neurons (in green) co-cultured with iPSC-derived astrocytes (in red). [VIB] Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s ...

Dopamine: It's not just for rewards anymore. In a new Northwestern University-led study, researchers identified and recorded from three genetic subtypes of dopamine neurons in the midbrain region of a ...

After a decade out of the spotlight, the brain cells once alleged to explain empathy, autism and theory of mind are being refined and redefined. In the summer of 1991, the neuroscientist Vittorio ...

Altering a protein in the neurons that coordinate a rattlesnake’s movement made a slow slither neuron more like a speedy rattle neuron, showing one way evolution can generate new ways of moving. In ...

For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside cells. But how these molecular vehicles identify and bind to the right cargo ...

LA JOLLA, CA—Gastrointestinal and digestive issues impact roughly 3 million people across the United States alone, and that number is growing. A new study from Scripps Research scientists shows how ...