Neuroscientists from Johns Hopkins Medicine say they have determined how a brain cell surface molecule shapes the way certain neurons behave. The research, published October 2 in Nature, reveals how a ...

Neuronal pathways originating from the orbitofrontal cortex (OFC) of the brain participate in different adaptive behaviors, but which pathways are used for distinct adaptive strategies remains unclear ...

Overview of the study. Researchers investigated the neural basis of how animals adapt to new environments and situations. To do this, they introduced a chemical ON/OFF switch in the orbitofrontal ...

A sequence of stress signals among specialized clean-up cells in the brain could at last reveal why some immune responses can cause significant nerve degeneration that results in the loss of memory, ...

Cell adhesion molecules (CAMS), i.e., laminin-1 or N-cadhedrin Adhesion and attractant Allow cells to grow along the surfaces of other cells (such as using pioneering axons for subsequent axons) ...

As detailed in a Stanford-led study published in Nature, researchers successfully created a replica of a neuronal pathway responsible for pain transmission in a lab dish called an “assembloid.” The ...

In a study published in European Heart Journal on December 26, a research team from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of ...

Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...

Quick-acting targeted therapies with minimal side effects are an urgent need for the treatment of anxiety-related disorders. While delta opioid receptor (DOP) agonists have shown 'anxiolytic' or ...

Medical University of South Carolina scientists report in Neuron that they have uncovered a way to restore an opioid-weakened brain pathway in a preclinical model. With funding from the National ...