本综述提出通过分析层次化观察数据的方法，量化临床实践变异性（Practice Variability），以优化循证实践（EBP）在重症医学领域的实施策略。作者结合预防和早期治疗急性肺损伤网络（PETAL）的机械通气患者数据，阐述了该方法在确定实践影响因素、评估证据生成 ...

Gamma Gap: A Point-of-Care Test That Correlates With Disease Burden and Treatment Response in Multiple Myeloma A total of 12,221 patients (median age, 75.6 years; 40.9% women, 87.6% white) were ...

Objectives To examine how the population composition, practice organisation and geographical context of general practice clinics are associated with unwarranted variation in prescribing patterns ...

Standardized clinical assessment and management plans are an alternative to clinical practice guidelines that reduce practice variability while allowing for physicians to adapt practices when ...

Glenview, Illinois – The American College of Chest Physicians ® (CHEST) recently released a new clinical guideline on the perioperative management of antithrombotic therapy. Published in the journal ...

NCCN guidelines are evidence-informed, consensus-driven, and influential in US payer policies, with a focus on multidisciplinary representation and global adaptations. ESMO guidelines reduce care ...