食管鳞癌（ESCC）占食管癌90%，早期治疗依赖内镜切除，但复发率高，缺乏特异靶向药物。液-液相分离（LLPS）在肿瘤中的作用日益受关注，但与ESCC关系不明。

总的来说，这项研究提供了大脑皮层中大量的 lncRNA 和 circRNA 及其相应的顺式表达数量性状基因座（cis-eQTL），这有助于更深入地理解大脑皮层中基因表达的遗传调控，并弥合大脑相关疾病遗传关联与其病理生理机制之间的差距。

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...

得益于雷根斯堡在RNA生物学方面的专业知识、其独特的菌株库以及在培养嗜极古菌方面的专门技术，这项新技术被证明特别有效。因此，在本研究中，能够使用到最适生长温度高达113°C的超嗜热古菌世界纪录保持者。

Our results demonstrate that differential connectivity analysis reveals significant transcriptional alterations that are not ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

本研究针对血吸虫病治疗药物单一、耐药性风险高等问题，系统开展了非寄生虫基因组编码RNA (ngRNA)在日本血吸虫 (S.japonicum)致病性调控中的作用研究。研究人员通过宏转录组学、单细胞RNA测序等技术，首次发现4种ngRNA通过编码RNA依赖性RNA聚合酶 (RdRp)调控血吸虫卵巢发育和产卵过程，并证实靶向rp1 ...

Eight years ago, 10x Genomics launched the first commercially available single-cell RNA sequencing (scRNA-seq) product for the company’s flagship instrument, the 10x Chromium. (This occurred one year ...

At the core of CTOAM's work, Morand explains, is a precision oncology process that integrates multiple diagnostic tools into ...