Illustrations are given of how a binomial sample-size table of limited scope can be used to address a wider range of problems. Necessary sample sizes for binomial differences not specifically covered ...

Sample sizes for single-stage phase II clinical trials in the literature are often based on exact (binomial) tests with levels of significance (alpha (α) <5% and power >80%). This is because there is ...

Implementation of the Time-to-Event Continuous Reassessment Method Design in a Phase I Platform Trial Testing Novel Radiotherapy-Drug Combinations—CONCORDE BayeSize applies the concept of effect size ...

When particles in a sample are the same size, one particle can be measured to report the result. If the sample has a narrow distribution, such as 10-25 µm, then measurement of just a few particles can ...

Cover Story - Packaging Sterile Packaging: Sample Sizes and Statistics Determining appropriate sample sizes for operational qualifications can help manufacturers ensure sterility of medical device ...