Significance testing, with appropriate multiple testing correction, is currently the most convenient method for summarizing the evidence for association between a disease and a genetic variant.

Chapter 5 argued that substantial improvements in the cost-effectiveness of operational testing can be achieved by test planning and state-of-the-art statistical methods for test design. It was also ...

NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of ...

Statistical significance is a critical concept in data analysis and research. In essence, it’s a measure that allows researchers to assess whether the results of an experiment or study are due to ...

The books Lies, Damn Lies, and Statistics (Wheeler, 1976) and Damned Lies and Statistics (Best, 2001) have raised questions about whether statistics can be trusted. A number of educated people today, ...

Methods of measuring statistical test sensitivity (signal-to-noise ratio) were published by John Mandel in 1964 and incorporated into ASTM D6600 in 2000, mainly to provide a means of determining the ...