After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to ...

The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose ...

Researchers have developed a comprehensive atlas that maps DNA methylation—a critical chemical modification governing gene activity—across 39 human cell types, revealing a complex landscape of ...

This image depicts the detection of structural variants (SVs) at low sequencing coverage in both unique and repetitive regions by genomic proximity mapping (GPM), compared with other SV-calling ...

A new genome-wide mapping method finally shows how thousands of genes connect to drive disease. Biomedical researchers are working intensively to identify the genes that contribute to disease, with ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

Scientists depicted the four-dimensional genome model to reveal how DNA folding regulates genes. The discovery helps ...

DNA's double helix has long stood as the symbol of life’s code. But buried within the genome lies a deeper level of complexity. One of the more intriguing discoveries in recent years is the i-motif—a ...

When scientists want to trace how a species has changed over time—and predict its prospects for survival—they turn to DNA. But what if the genetic map guiding them belongs to the wrong animal? Lycium ...

One of the biggest quests in biology is understanding how every cell in an animal's body carries an identical genome yet ...