The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose ...

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to map the 3D organization of the human genome and how it changes over time, ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

DNA's double helix has long stood as the symbol of life’s code. But buried within the genome lies a deeper level of complexity. One of the more intriguing discoveries in recent years is the i-motif—a ...

A new genome-wide mapping method finally shows how thousands of genes connect to drive disease. Biomedical researchers are working intensively to identify the genes that contribute to disease, with ...

Scientists depicted the four-dimensional genome model to reveal how DNA folding regulates genes. The discovery helps ...

Large-scale human genetics studies have shown that many risk variants for common and complex diseases sit in the non-coding genome, where they can alter ...

Sometimes, a small error in the sequence of DNA can lead to a very serious disease. Scientists have identified many mutations ...

One of the biggest quests in biology is understanding how every cell in an animal's body carries an identical genome yet ...

For decades, geneticists have known that most common illnesses are not caused by a single rogue gene but by intricate ...