为解决造血祖细胞(HPCs)和单核细胞(MNCs)在临床储存中的稳定性问题,研究人员通过多组学分析评估了4℃条件下0-4天的细胞表型与转录组变化。结果显示HPCs在24小时内即出现显著转录组改变,而MNCs表型稳定长达4天。该研究为细胞治疗产品的质量控制窗口提供了 ...
导读:肝祖细胞(HPCs)具有肝脏再生的巨大潜力,但它们众所周知的增殖限制阻碍了它们的更广泛使用。有证据表明,HPCs的增殖需要层粘连蛋白,但起主导作用的层粘连蛋白亚型和介导HPC增殖调控的关键细胞内下游靶标尚未确定。 8月31日,华中科技大学陈孝平 ...
The study investigates the role of autophagy in hepatic progenitor cells (HPCs) and its potential to modulate exosomal microRNAs (miRNAs) to inhibit liver fibrosis in the context of schistosomiasis, a ...
On the basis of the controversial data about the clinical relevance of NG2 expression and its inclusion in diagnostic immunophenotypic panels as well as the existence of NG2-expressing acute leukemias ...
As discussed here earlier this year, the DARPA HPCS program has had a lot of positive publicity about its focus on usability and productivity in HPC systems. The question of how to evaluate HPC ...