The stakes are high for several teams in the penultimate week of the NFL regular season. Here's how the odds see it going.

The NFL season continues in Week 16 when the Cleveland Browns host the Buffalo Bills on Sunday. Start time, how to watch, stream and NFL TV schedule.

There are four ways Buffalo can clinch a playoff berth here in Week 16. The first (and the most probable) comes with a win over the Browns, and an Indianapolis Colts loss or tie against the San Francisco 49ers on Monday Night Football. While that game is in Indianapolis, the visiting 49ers are favored.

Myles Garrett entered Sunday's game against the Bills within reach of breaking the NFL's single-season sack record.

The Buffalo Bills haven’t had an NFL rushing leader since O.J. Simpson in the 1970s, but James Cook came one step closer to doing that on Sunday. On Buffalo’s opening drive, he went 67 yards including a 44-yard touchdown. On the run, he moved past Jonathan Taylor for the league lead in rushing yards.

Allen completed 12 of 19 passes for just 130 yards, as Buffalo again relied heavily on the ground game. James Cook rushed 16 times for 117 yards and two touchdowns, while Ty Johnson added a rushing touchdown as well. Veteran safety Jordan Poyer stood out defensively with 11 tackles, one pass defensed and half a sack.

Despite losing 14 pounds from illness, Dawkins helped contain Garrett who remains 1 sack away from breaking the NFL single-season record.