Chemical modifications of human ribosomal RNA (rRNA) are introduced during biogenesis and have been implicated in the dysregulation of protein synthesis, as is found in cancer and other diseases.

ERA, composed of an N-terminal GTPase domain followed by an RNA-binding KH domain, is essential for bacterial celi viability. It binds to 16S rRNA and the 30S ribosomal subunit. However, its ...