When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular aging, cancer, ...

The first step in DNA replication requires the assembly of a group of proteins called the Origin Recognition Complex (ORC). Researchers have determined how the ORC assembles during the cell division ...

Unlike nuclear DNA, mitochondrial DNA (mtDNA) is circular in nature and organized as mitochondrial nucleoids comprised of DNA-protein complexes that are distributed in the matrix. It is also inherited ...

To better understand BKPyV replication and ways to prevent it, researchers in the UAB Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney cells. Their ...

Your support goes further this holiday season. When you buy an annual membership or give a one-time contribution, we’ll give a membership to someone who can’t afford access. It’s a simple way for you ...

“The first principle is that you must not fool yourself — and you are the easiest person to fool,” physicist Richard Feynman famously told the young scientists graduating from CalTech in 1974. Fully ...

Tech giants dominate research but the line between real breakthrough and product showcase can be fuzzy. Some scientists have had enough. Last month Nature published a damning response written by 31 ...