Triglia discusses her research at the intersection of genetics, epigenetics, single-cell genomics and computational biology.

Analysis of proteins is not simple. Unlike DNA, there is incredible diversity in the concentration and variety of proteins created by a cell at any given moment. In our Proteomics Playbook we outline ...

Why is sample preparation important? Increasingly, NGS is being asked to handle more challenging samples, from diverse origins, of lower quality or of small size. Before these samples can be analyzed, ...

Illumina’s systems employ short-read sequencing techniques, which has been the predominant NGS technology for the last decade. The company has made huge advances in the NGS space and now markets a ...

Single-cell transcriptomics, or scRNA-seq, is widely used for analysing the transcriptome of single-cell populations. With scRNA-seq, gene expression profiling can explore genotype-phenotype ...

The idea that the experiences of our ancestors shape who we are today is not a novel one. In fact, throughout history, great thinkers from around the world have proposed theories and ideas to explain ...

As advancements in genetic technologies accelerate at an astonishing pace, the potential for gene editing to transform our world becomes closer to being realised. With the advent of revolutionary ...

Written by Arpita Kulkarni (Director of the Functional Genomics and Bioinformatics Core at HMS/BIDMC). Across the life sciences, a quiet anxiety is growing: what is the role of the experimental ...

Nucleic acid sequencing has become an integral part of modern biomedical research. The advances in sequencing technology, from its invention to modern-day equivalents, have been extraordinary. 2022 ...

Since the discovery of the basic double-helix structure of DNA In the 1950’s, scientists have devoted a huge amount of effort to determine the sequence of a variety of different genomics. It took over ...

Two things that have defined the 21 st century are genomics and the internet. Through a combination of these has emerged a controversial type of ‘influencer’ on the internet – self-gene-editors or ...

Diversity in research has been a hot topic in this week’s news… ...