Week 16 of the NFL season winds down this evening with the San Francisco 49ers traveling cross-country to take on the ...

The Indianapolis Colts host the San Francisco 49ers on "Monday Night Football": Inactives, injury report, who's in, who's out ...

The Sporting News is tracking live scoring updates and highlights for 49ers vs. Colts on "Monday Night Football." Follow for complete results from the NFL Week 16 prime-time game.

Follow live coverage as Indianapolis attempts to salvage its playoff hopes, hosting San Francisco on "Monday Night Football" ...

The Chargers have won 11 games and are still in the hunt for an AFC West title. That doesn’t mean they are Super Bowl ready ...

Week 16 comes to a close with a “Monday Night Football” matchup featuring the San Francisco 49ers (10-4) and the Indianapolis ...

The Indianapolis Colts are looking to snap a four-game losing streak and get back into the AFC playoff picture Monday night.

Oct 19, 2025; Inglewood, California, USA; Indianapolis Colts offensive tackle Bernhard Raimann (79) blocks Los Angeles Chargers linebacker Tuli Tuipulotu (45) in the first half at SoFi Stadium.

San Francisco aims to improve playoff position while Indianapolis fights for postseason hopes with Philip Rivers at ...

NFL Week 17 power rankings are here. Who's ranked No. 1? Where are Bears, Seahawks, Patriots after wins? Week 17 NFL power rankings for all 32 teams.

Pro Bowl defensive tackle DeForest Buckner was activated off injured reserve Monday and will play for the Indianapolis Colts ...

NFL Week 17 predictions, picks for games this week, including Broncos-Chiefs, Eagles-Bills, Bears-49ers, Rams-Falcons, Ravens-Packers, Giants-Raiders.