BMJ Evidence-Based Medicine

Reporting GUideline for Intervention DEscription in Rehabilitation (GUIDE-Rehab): a tool to open the ‘black box’ of rehabilitation complex interventions

In 2023, the World Health Assembly adopted a resolution to strengthen rehabilitation within health systems, calling for ...
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Current knowledge on the adaptation of clinical practice guidelines: a scoping review

Background The adaptation of clinical practice guidelines (CPGs) is increasingly used to efficiently develop contextualised recommendations for local, regional and national settings. However, ...
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Regression to the mean: a primer for evidence-based medicine practitioners

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Rapid reviews methods series: Guidance on literature search

This paper is part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group. Rapid reviews (RR) use modified systematic review methods to accelerate the review process ...
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Less is more - but for whom? Evaluating patient reported outcomes in de-implementation

All over the world, patients receive healthcare that has little to no benefit, also called low-value care. There have been an increasing number of initiatives to reduce, or de-implement, low-value ...
Opinion
BMJ Evidence-Based MedicineOpinion

Ataluren for Duchenne: how politics and social pressure undermined evidence-based decisions

Last 28 March 2025, the European Commission decided not to renew the conditional marketing authorisation for Translarna (ataluren) in Duchenne’s disease due to lack of efficacy after 11 years in the ...
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Evidence based medicine manifesto for better healthcare

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How good is the evidence to support primary care practice?

Correspondence to Dr Mark H Ebell, Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, 125 Miller Hall, UGA Health Sciences Campus, Athens, GA 30602, USA; ...
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Potential risks of GenAI on medical education

Generative artificial intelligence (AI) moved from an experimental novelty into mainstream use as an everyday tool in under 3 years. Large language models (LLMs) now pass portions of knowledge ...
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Methodological quality and synthesis of case series and case reports

Correspondence to Dr Mohammad Hassan Murad, Evidence-Based Practice Center, Mayo Clinic, Rochester, MN 55905, USA; murad.mohammad{at}mayo.edu In 1904, Dr James Herrick evaluated a 20-year-old patient ...
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Leading with options or issues to support purposeful shared decision-making in clinical practice

Shared decision-making (SDM) is the process by which patients and clinicians work together to cocreate care plans that respond to the patient’s problematic situation.1 2 In daily life, a familiar ...