Colts injury report as Ricky Pearsall misses a second straight practice while McCaffrey and Trent Williams return ahead of Week 16.

Kyle Shanahan says WR Ricky Pearsall could play vs. the Colts despite missing practice as San Francisco eyes a playoff-clinching win.

The Indianapolis Colts and San Francisco 49ers face off in "Monday Night Football" this week. Check out how to watch on ...

The San Francisco 49ers held onto the No. 6 seed in the NFC playoff picture with a convincing 37-24 victory over the ...

The 49ers will take on the Colts on Monday, and they'll likely face Philip Rivers. Here's what Kyle Shanahan had to say about the ...

The Seahawks were the big winners on Thursday night, moving to 12-3 and opening up a one-game lead over the 11-4 Rams for the NFC West title and the No.

PFF's media research team has been hard at work preparing for kickoff by pulling data-driven insights and talking points for our broadcast partners around ...

GM John Lynch defends WR Ricky Pearsall, pushing back on the injury-prone label as San Francisco prepares for a pivotal game vs. Colts.

CBS Sports predicts Philip Rivers will throw for 300 yards against the 49ers on MNF as San Francisco looks to clinch a playoff spot.

John Lynch says the 49ers are focused on beating the Colts and clinching a playoff spot, not the Brandon Aiyuk saga or NFC seeding.

Broadcast and streaming information for the San Francisco 49ers Week 16 'Monday Night Football' matchup against the Indianapolis Colts at Lucas ...

The 49ers have won their last four games since Brock Purdy returned to the lineup, and Troy Aikman says the quarterback is playing his ...