NFL reporter Omar Ruiz gives the playoff implication of the San Francisco 49ers vs. the Indianapolis Colts..

The San Francisco 49ers are getting to a better place on the injury front, but wide receiver Ricky Pearsall is still ...

The 49ers remain focused on the Colts as playoff stakes rise, with Kyle Shanahan and Brock Purdy preaching a week-to-week approach.

The San Francisco 49ers are headed to Indianapolis for a Week 16 matchup against the Colts, and they now officially know who they'll be facing under center. While it was expected that quarterback ...

San Francisco 49ers defensive coordinator Robert Saleh, offensive coordinator Klay Kubiak, and quarterback Brock Purdy spoke to reporters after ...

Colts injury report as Ricky Pearsall misses a second straight practice while McCaffrey and Trent Williams return ahead of Week 16.

Kyle Shanahan says WR Ricky Pearsall could play vs. the Colts despite missing practice as San Francisco eyes a playoff-clinching win.

The Indianapolis Colts and San Francisco 49ers face off in "Monday Night Football" this week. Check out how to watch on ...

The San Francisco 49ers held onto the No. 6 seed in the NFC playoff picture with a convincing 37-24 victory over the ...

The 49ers will take on the Colts on Monday, and they'll likely face Philip Rivers. Here's what Kyle Shanahan had to say about the ...

The Seahawks were the big winners on Thursday night, moving to 12-3 and opening up a one-game lead over the 11-4 Rams for the NFC West title and the No.

PFF's media research team has been hard at work preparing for kickoff by pulling data-driven insights and talking points for our broadcast partners around ...