Given CpGPT's generative capabilities, we have implemented an analogous version of the chain-of-thought used in NLP tasks but for the reconstruction of methylation patterns. For more information about ...

For decades, biology textbooks taught that DNA’s story could be told with a single image: two elegant strands twisting in a ...

Can life exist without the very metabolic machinery that defines it? The discovery of Candidatus Sukunaarchaeum mirabile ...

This work provides high-precision single-cell data on the relationship between DnaA activity and cell size, offering important insights for the field of cell cycle control. These findings motivate a ...

DNA replication is a semi-conservative process in which half of the newly synthesized strands (daughters) are derived from the original strands (mothers). The confirmation of semi-conservative ...

In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

This valuable descriptive manuscript builds on prior research showing that the elimination of Origin Recognition Complex (ORC) subunits does not halt DNA replication. The authors obtain solid data ...

The discovery of DNA ligase by the Gellert, Lehman, Richardson, and Hurwitz teams in 1967 was a breakthrough in molecular biology. These essential enzymes maintain genome integrity and play a vital ...

DNA is the molecular basis of heredity, the inherited traits that pass between generations in a person's family tree. Embodied in the sequence of base pairs, DNA carries information between ...

DNA replication is one of the most well-orchestrated cellular processes that needs to proceed in a faithful and timely manner. However, this process is continuously challenged, leading to stalled ...

Single-cell analysis helps uncover how the BK virus replicates, opening the door to new drug targets. BK polyomavirus (BKPyV) is a major cause of kidney transplant failure. Without a complete ...