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Purdy, Indianapolis Colts and 49ers

Brock Purdy's career-high five TD passes power 49ers past Philip Rivers' Colts on 'Monday Night Football'

The Week 16 edition of "Monday Night Football" between the Indianapolis Colts (8-7) and the San Francisco 49ers (11-4) will be remembered as the Brock Purdy game.

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Brock Purdy throws five TDs as 49ers outgun Colts in 48-27 scoreboard bonanza

· 4h · on MSN

Brock Purdy, San Francisco surging at right time: Colts vs. 49ers MNF takeaways

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Philip Rivers starts strong, but his late Pick-6 proves costly to Colts' playoff hopes in 48-27 loss

Quarterback Philip Rivers came out of retirement seeking to lead the Indianapolis Colts to the playoffs.

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San Francisco 49ers vs Indianapolis Colts recap today: Purdy's huge night buries Colts

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49ers thrash Colts behind Purdy’s 5 TD passes: Live updates and reaction from NFL ‘Monday Night Football’

· 23h

Why Philip Rivers is the Colts best quarterback option vs. the 49ers

The Colts hold single-digit odds to make the playoffs with three games to go, needing two, if not three wins, to find their way into the AFC playoff picture.

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Best MNF Player Prop Bets, Latest Odds for 49ers at Colts in Week 16

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Experts release surprising MNF predictions for Philip Rivers against 49ers’ defense

Indianapolis Colts go with Philip Rivers again

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· 1h · on MSN

Philip Rivers does his part but Colts humbled in loss to 49ers

Newly unretired Philip Rivers turned in an impressive individual performance Monday night that saw him throw for 277 yards and two touchdowns. But it wasn't enough to deliver the Colts a win against the 49ers as Indianapolis saw its playoff hopes fade.

· 3h · on MSN

Philip Rivers starts strong, but his late pick-6 proves costly to Colts' playoff hopes in 48-27 loss

· 1d · on MSN

NFL expert picks today against the spread: Indianapolis Colts go with Philip Rivers again

4hon MSN

Colts playoff picture: Scenarios, chances for Indianapolis to make postseason

The Colts are in danger of missing the postseason after a strong start to the 2025 regular season. Here are their playoff scenarios after Week 16.

Colts Wire on MSN

3 takeaways from latest Indianapolis Colts loss to 49ers

Following the Indianapolis Colts' performance on Monday Night Football, here are three takeaways from what took place against the 49ers.

19mon MSN

The 7 Biggest Takeaways From the 49ers' Win Against Indianapolis

Another win stacked up by the San Francisco 49ers. Their offense lit up the Indianapolis Colts in primetime to get the win with a score of 48-27. It was amazing

Buffalo Bills fan discussion: Playoff picture chat with Indianapolis Colts on ‘Monday Night Football’

The San Francisco 49ers still have a chance to claim the one seed in the NFC playoff bracket with a win in Week 16 over the Indianapolis Colts.

3hon MSN

49ers fans thinking Super Bowl after commanding MNF win over Colts

Brock Purdy and the San Francisco 49ers made it look easy against the Indianapolis Colts on "Monday Night Football."

WISH-TV

8 must-read quotes from the Colts loss to the 49ers

INDIANAPOLIS (WISH) — The Colts lost to the 49ers, 48-27. The loss dropped the team’s record to 8-7 and marked their fifth straight loss. Here are eight quotes that told the story of the game:

2hon MSN

Colts Rookie Exits Early vs. 49ers

The more impactful injury is Bortolini, who's since been replaced by Danny Pinter at the heart of the offensive line. The Colts are now down to three backup offensive linemen, a less-than-ideal situation for a team looking to make a playoff push.

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Jaguars vs Colts picks, predictions, odds for NFL Week 17 game Sunday

NFL Week 17 odds, picks, predictions, TV channel, streaming information for Sunday football game between Jacksonville Jaguars and Indianapolis Colts.