The 49ers have arguably the toughest two-game closing stretch among the teams in playoff positions. They face the Chicago ...

San Francisco already clinched a playoff berth but finds itself in the thick of the NFC West and wild card races.

The 49ers face the Colts in Indianapolis on Monday. We break down what the game means for the NFL playoff picture.

Philip Rivers, the grandfather and former Pro Football Hall of Fame semifinalist, came out of retirement to play for the ...

Who is in the NFL playoffs? Seven teams have now clinched berths in field with Patriots, 49ers, Eagles, Bears, Seahawks clinching berths in Week 16.

Three more teams are playoff-bound after Monday's contest between the San Francisco 49ers and the Indianapolis Colts.

The Indianapolis Colts lose to the San Francisco 49ers in NFL Week 16 action on 'Monday Night Football': Score updates, highlights ...

As a result of the Indianapolis Colts losing their Week 16 matchup with the San Francisco 49ers on Monday Night Football, the ...

The Week 16 edition of "Monday Night Football" between the Indianapolis Colts (8-7) and the San Francisco 49ers (11-4) will ...

Philip Rivers starts again when he takes on the ferocious 49ers on "Monday Night Football." Here's score, highlights, stats and more for Colts-49ers.

SAN FRANCISCO, Calif. - The San Francisco 49ers secured a spot in the playoffs following the Detroit Lions' loss to the ...

Brock Purdy was a vastly different quarterback on Monday night against the Colts compared to his prior Monday Night Football ...