San Francisco 49ers quarterback Brock Purdy made NFL history with the team's double-digit win over the Indianapolis Colts in ...

Brock Purdy threw a career-high five touchdown passes and Dee Winters returned an interception 74 yards for a score to lead ...

The San Francisco 49ers needed to win their final three games to clinch the No. 1 seed in the NFC playoffs. Things got off to ...

Something Purdy had in common with 44-year-old Philip Rivers on Monday — mental sharpness, which came in handy in a big ...

San Francisco 49ers head coach Kyle Shanahan had strong praise for quarterback Brock Purdy after Monday night's 48-27 win ...

The Indianapolis Colts lose to the San Francisco 49ers in NFL Week 16 action on 'Monday Night Football': Score updates, ...

Philip Rivers starts again when he takes on the ferocious 49ers on "Monday Night Football." Here's score, highlights, stats ...

Two more wins to the 1 seed. Brock Purdy threw a career-high five touchdown passes as the Niners' offense could not be ...

Brock Purdy threw a career-high five touchdown passes, two to running back Christian McCaffrey, and the San Francisco 49ers ...

The Week 16 edition of "Monday Night Football" between the Indianapolis Colts (8-7) and the San Francisco 49ers (11-4) will ...

The San Francisco 49ers are going to make the playoffs, but there are not many people who believe that they are legitimate ...

Brock Purdy had plenty of respect after sharing the field with 44-year-old Philip Rivers on Monday night. The San Francisco ...