1Division of Hematology, Brigham and Women’s Hospital, Boston, Massachusetts. 2Department of Medicine, Harvard Medical School, Boston, Massachusetts. 3Broad ...

Major Finding: TET2-mutant clonal hematopoiesis alters macrophages to facilitate improved immunotherapy response. Concept: TET2-mutant macrophages are immunogenic, antigen-presenting cells that prime ...

1Koch Institute for Integrative Cancer Research, Massachusetts Institute for Technology, Cambridge, Massachusetts. 2Department of Biological Engineering, Massachusetts Institute for Technology, ...